NMR-BASED METABOLOMIC ANALYSIS OF CARDIAC TISSUES CLARIFIES MOLECULAR MECHANISMS OF CVB3-INDUCED VIRAL MYOCARDITIS AND DILATED CARDIOMYOPATHY

NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy

Viral myocarditis (VMC), which is defined as inflammation of the myocardium with consequent myocardial injury, may develop chronic disease eventually leading to dilated cardiomyopathy (DCM).Molecular mechanisms underlying the progression from Synthetic Lace Part Wig acute VMC (aVMC), to chronic VMC (cVMC) and finally to DCM, are still unclear.Here,

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The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

Low density lipoprotein (LDL) cholesterol is taken up into cells via clathrin-mediated endocytosis of the LDL receptor (LDLR).Following dissociation of the LDLR-LDL complex, LDL is directed to lysosomes whereas the LDLR recycles to the plasma membrane.Activation of the sterol-sensing nuclear receptors liver X receptors (LXRs) enhances degradation o

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Detection of Wideband Signal Number Based on Bootstrap Resampling

Knowing source number Mats correctly is the precondition for most spatial spectrum estimation methods; however, many snapshots are needed when we determine number of wideband signals.Therefore, a new method based on Bootstrap resampling is proposed in this paper.First, signals are divided into some nonoverlapping subbands; apply coherent signal met

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Genomic Analyses of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus pseudintermedius Strains Involved in Canine Infections: A Comprehensive Genotypic Characterization

Staphylococcus pseudintermedius is frequently associated with several bacterial infections in Feature dogs, highlighting a One Health concern due to the zoonotic potential.Given the clinical significance of this pathogen, we performed comprehensive genomic analyses of 28 S.pseudintermedius strains isolated from canine infections throughout whole-ge

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